Issue 3, 2012
From the journal:

Nanoscale

FRET-mediated pH-responsive dual fluorescent nanoparticles prepared via click chemistry†

Karima Ouadahi,a   Kamal Sbargoud,a   Emmanuel Allarda  and  Chantal Larpent*a  

* Corresponding authors

a Institut Lavoisier de Versailles UMR-CNRS 8180, Université de Versailles-Saint-Quentin-en-Yvelines, 45 Avenue des Etats-Unis, Versailles Cedex, France
E-mail: Larpent@chimie.uvsq.fr
Fax: +33 139 254 452
Tel: +33 139 254 413

Abstract

Herein, we report an easy preparation of azide-coated polystyrene-based nanoparticles (15 nm in diameter) and their surface functionalization viaCuAAC with fluorophores in water. Resultant dual fluorescent nanoparticles coated with dansyl and pH-sensitive fluorescein moieties as the donor/acceptor FRET pair show a ratiometric response to pH upon excitation at a single wavelength.

Graphical abstract: FRET-mediated pH-responsive dual fluorescent nanoparticles prepared via click chemistry

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Article information

DOI
https://doi.org/10.1039/C2NR11413E
Article type
Communication
Submitted
28 Sep 2011
Accepted
24 Nov 2011
First published
16 Dec 2011

Nanoscale, 2012,4, 727-732

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FRET-mediated pH-responsive dual fluorescent nanoparticles prepared via click chemistry

K. Ouadahi, K. Sbargoud, E. Allard and C. Larpent, Nanoscale, 2012, 4, 727 DOI: 10.1039/C2NR11413E

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