Issue 62, 2012
From the journal:

Chemical Communications

Development of reversible fluorescence probes based on redox oxoammonium cation for hypobromous acid detection in living cells†

Fabiao Yu,ab   Ping Song,a   Peng Li,a   Bingshuai Wanga  and  Keli Han*a  

* Corresponding authors

a State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, CAS, P. R. China
E-mail: klhan@dicp.ac.cn

b School of Chemical Engineering, Dalian University of Technology, 2 Linggong Road, Dalian, 116024, P. R. China
E-mail: yufabiao@163.com

Abstract

We describe the synthesis, properties, and application of two reversible fluorescent probes, mCy-TemOH and Cy-TemOH, for HOBr sensing and imaging in live cells. The two probes contain a hydroxylamine functional group for the monitoring of HOBr oxidation/ascorbic acid reduction events. Confocal fluorescence microscopy has established the HOBr detection in live-cells.

Graphical abstract: Development of reversible fluorescence probes based on redox oxoammonium cation for hypobromous acid detection in living cells

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Article information

DOI
https://doi.org/10.1039/C2CC33264G
Article type
Communication
Submitted
07 May 2012
Accepted
12 Jun 2012
First published
13 Jun 2012

Chem. Commun., 2012,48, 7735-7737

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Development of reversible fluorescence probes based on redox oxoammonium cation for hypobromous acid detection in living cells

F. Yu, P. Song, P. Li, B. Wang and K. Han, Chem. Commun., 2012, 48, 7735 DOI: 10.1039/C2CC33264G

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