Issue 14, 2012
From the journal:

Analyst

Detection of the cell viability and proliferation using two-signal electrochemical method†

Jing-Tao Wang,a   Li-Ya Ge,b   Xing Yuan,c   Zhe-Feng Wang,b   Jin-Lian Li,b   Xiao-Ling Guo,b   Dong-Mei Wu*b  and  Ji-Guang Liu*a  

* Corresponding authors

a School of Medicine, Jiamusi University, Jiamusi, China
E-mail: liujg5550@163.com
Fax: +86 454 8618460
Tel: +86 454 8618461

b College of Pharmacy, Jiamusi University, Jiamusi, China
E-mail: wudmei@yahoo.com.cn

c College of Urban and Environmental Science, Northeast Normal University, Changchun, China

Abstract

Two electrochemical signals of the MCF-7 cell were simultaneously detected by using multiwall carbon nanotubes and room temperature ionic liquid composite film modified electrode. The signal at +0.726 V due to the oxidation of xanthine and guanine, was obviously improved. And the signal at +1.053 V due to the oxidation of hypoxanthine and adenine was found for the first time. This two-signal electrochemical method is credible to detect cell viability and proliferation.

Graphical abstract: Detection of the cell viability and proliferation using two-signal electrochemical method

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Supplementary files

Article information

DOI
https://doi.org/10.1039/C2AN35076A
Article type
Communication
Submitted
15 Jan 2012
Accepted
25 Apr 2012
First published
25 Apr 2012

Analyst, 2012,137, 3230-3233

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Detection of the cell viability and proliferation using two-signal electrochemical method

J. Wang, L. Ge, X. Yuan, Z. Wang, J. Li, X. Guo, D. Wu and J. Liu, Analyst, 2012, 137, 3230 DOI: 10.1039/C2AN35076A

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