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Issue 3, 2011
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Mobility of fluorescently labeled polymer micelles in living cells

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Abstract

Stabilized fluorescent polymeric micelles were made that are spontaneously taken up into the cytoplasm of human cells. The mobility of these micelles in living cells was probed on a molecular level for the first time with FCS. Importantly, the present micelles do not interact with proteins, membranes or cellular organelles. This system provides a new nanotechnological tool which is biocompatible, versatile and easy to use, especially since after further chemical modification, they could be targeted to specific subcellular locations.

Graphical abstract: Mobility of fluorescently labeled polymer micelles in living cells

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Publication details

The article was received on 18 Aug 2010, accepted on 27 Nov 2010 and first published on 20 Dec 2010


Article type: Paper
DOI: 10.1039/C0SM00835D
Citation: Soft Matter, 2011,7, 1214-1218
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    Mobility of fluorescently labeled polymer micelles in living cells

    F. Li, A. H. Westphal, A. T. M. Marcelis, E. J. R. Sudhölter, M. A. Cohen Stuart and F. A. M. Leermakers, Soft Matter, 2011, 7, 1214
    DOI: 10.1039/C0SM00835D

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