Issue 13, 2011
From the journal:

Organic & Biomolecular Chemistry

Amperometric detection of antibodies in serum: performance of self-assembled cyclodextrin/cellulose polymer interfaces as antigen carriers†

Mayreli Ortiz,a   Alex Fragoso*a  and  Ciara K. O'Sullivan*ab  

* Corresponding authors

a Nanobiotechnology & Bioanalysis Group, Departament d'Enginyeria Química, Universitat Rovira i Virgili, Avinguda Països Catalans 26, Tarragona, Spain
E-mail: alex.fragoso@urv.cat, ciara.osullivan@urv.cat

b Institució Catalana de Recerca i Estudis Avançats, Passeig Lluis Campanys, 23, Barcelona, Spain

Abstract

A bifunctionalised carboxymethyl-cellulose polymer bearing adamantane units and an antigenic fragment forms a highly stable interfacial complex with a βCD-containing surface. This allows the highly sensitive detection of antibodies using an amperometric immunosensor.

Graphical abstract: Amperometric detection of antibodies in serum: performance of self-assembled cyclodextrin/cellulose polymer interfaces as antigen carriers

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Article information

DOI
https://doi.org/10.1039/C1OB05473B
Article type
Communication
Submitted
25 Mar 2011
Accepted
12 May 2011
First published
13 May 2011

Org. Biomol. Chem., 2011,9, 4770-4773

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Amperometric detection of antibodies in serum: performance of self-assembled cyclodextrin/cellulose polymer interfaces as antigen carriers

M. Ortiz, A. Fragoso and C. K. O'Sullivan, Org. Biomol. Chem., 2011, 9, 4770 DOI: 10.1039/C1OB05473B

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