Issue 11, 2011

Triflic acid-mediated phenylation of N-acylaminoalkyl diethylacetals and N-acyl-2-phenyl cyclic amides

Abstract

The reaction of N-acylaminoalkyl diethylacetals with triflic acid in benzene gave N-acylamino-diphenylalkyls. The proposed intermediates are the N-acyl-2-phenyl cyclic amides, which themselves are similarly converted to N-acylamino-diphenylalkyls.

Graphical abstract: Triflic acid-mediated phenylation of N-acylaminoalkyl diethylacetals and N-acyl-2-phenyl cyclic amides

Supplementary files

Article information

Article type
Paper
Submitted
10 Dec 2010
Accepted
07 Mar 2011
First published
07 Mar 2011

Org. Biomol. Chem., 2011,9, 4361-4366

Triflic acid-mediated phenylation of N-acylaminoalkyl diethylacetals and N-acyl-2-phenyl cyclic amides

F. D. King and S. Caddick, Org. Biomol. Chem., 2011, 9, 4361 DOI: 10.1039/C0OB01149E

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