Jump to main content
Jump to site search

Issue 11, 2011
Previous Article Next Article

The sorbicillinoid family of natural products: Isolation, biosynthesis, and synthetic studies

Author affiliations

Abstract

Covering: 1948 up to the end of 2010

The sorbicillinoids are a family of hexaketide metabolites that have been isolated from a variety of fungal sources, collected from both marine and terrestrial sources. Since 1948, the family has grown in size to include over 50 members, many of which have complex, highly oxygenated, bicyclic and tricyclic frameworks. In conjunction with their biological activity, the structural complexity of these structures has inspired several synthetic campaigns and has also led to controversy surrounding the biosynthetic pathway responsible for the natural production of these compounds. Through this review, we aim to give a historical perspective to each of these areas and hope to inspire new avenues of research for addressing the knowledge gaps that still exist.

Graphical abstract: The sorbicillinoid family of natural products: Isolation, biosynthesis, and synthetic studies

Back to tab navigation

Publication details

The article was received on 03 May 2011 and first published on 16 Sep 2011


Article type: Review Article
DOI: 10.1039/C1NP00039J
Citation: Nat. Prod. Rep., 2011,28, 1790-1810
  •   Request permissions

    The sorbicillinoid family of natural products: Isolation, biosynthesis, and synthetic studies

    A. M. Harned and K. A. Volp, Nat. Prod. Rep., 2011, 28, 1790
    DOI: 10.1039/C1NP00039J

Search articles by author

Spotlight

Advertisements