Effects of Zn(II) complex with vitamins C and U, and carnitine on metabolic syndrome model rats

Kinuyo Matsumoto; Nao Motoyasu; Kyoko Sera; Takako Fujii; Yutaka Yoshikawa; Hiroyuki Yasui; Hiroshi Taniguchi; Naemi Kajiwara

doi:10.1039/C1MT00018G

Effects of Zn(ii) complex with vitamins C and U, and carnitine on metabolic syndrome model rats†

Kinuyo Matsumoto,*^a Nao Motoyasu,^a Kyoko Sera,^a Takako Fujii,^a Yutaka Yoshikawa,^b Hiroyuki Yasui,^b Hiroshi Taniguchi^ac and Naemi Kajiwara^a

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* Corresponding authors

^a Department of Sports, Health and Nutrition, Faculty of Health and Welfare, 4-7-2 Minatojim Nakamachi, Kobe 650-0046, Japan
E-mail: kinuyo.m@suma.kobe-wu.ac.jp
Fax: 81-78-737-2427
Tel: 81-78-737-2427

^b Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, Kyoto 607-8414, Japan

^c Yamato Institute of Lifestyle-related Diseases, Akashi 673-8688, Japan

Abstract

The insulinomimetic activity of a Zn(II) complex is reported. The effects of the Zn(II) complex with ascorbic acid (Vitamin C; VC), methylmethionine sulfonium chloride (Vitamin U; VU) and L-carnitine were assessed in diet-induced metabolic syndrome model rats. Zn(VU)₂Cl₂ and Zn(VC)Cl₂ were suggested to be useful supplementary materials for preventing metabolic syndrome by reducing visceral adipose tissues or accelerating blood fluidity.

This article is part of the themed collection: Metallomics in Japan

Metallomics

Effects of Zn(ii) complex with vitamins C and U, and carnitine on metabolic syndrome model rats†

Abstract

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