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Issue 12, 2011
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Micromolding of solvent resistant microfluidic devices

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We demonstrate a rapid fabrication procedure for solvent-resistant microfluidic devices based on the perfluoropolyether (PFPE) SIFEL. We carefully modified the poly-dimethylsiloxane (PDMS) micromolding procedure, such that it can still be executed using the standard facilities for PDMS devices. Most importantly, devices with a thin SIFEL layer for the patterned channels and a PDMS support layer on top offered the best of two worlds in terms of chemical and mechanical stability during fabrication and use. Tests revealed that these devices overcome two important drawbacks of PDMS devices: (i) incompatibility with almost all non-aqueous solvents, and (ii) leaching of oligomer into solution. The potential of our device is shown by performing a relevant organic synthesis reaction with aggressive reactants and solvents. PFPE-PDMS devices will greatly expand the application window of micromolded devices.

Graphical abstract: Micromolding of solvent resistant microfluidic devices

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The article was received on 01 Nov 2010, accepted on 03 May 2011 and first published on 11 May 2011

Article type: Technical Note
DOI: 10.1039/C0LC00550A
Citation: Lab Chip, 2011,11, 2035-2038
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    Micromolding of solvent resistant microfluidic devices

    T. J. A. Renckens, D. Janeliunas, H. van Vliet, J. H. van Esch, G. Mul and M. T. Kreutzer, Lab Chip, 2011, 11, 2035
    DOI: 10.1039/C0LC00550A

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