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Issue 12, 2011
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Multiple flow profiles for two-phase flow in single microfluidic channels through site-selective channel coating

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Abstract

An approach to control two-phase flow systems in a poly(dimethylsiloxane) (PDMS) microfluidic device using spatially selective surface modification is demonstrated. Side-by-side flows of ethanol : water solutions containing different polymers are used to selectively modify both sides of a channel by laminar flow patterning. Introduction of air pockets during modification allows for control over the length of the channel section that is modified. This approach makes it possible to achieve slug flow and side-by-side flow of water : 1-octanol simultaneously within the same PDMS channel, without the need of additional structural elements. A key finding is that conditioning of the PDMS channels with 1-octanol before polymer deposition is crucial to achieving stable side-by-side flows.

Graphical abstract: Multiple flow profiles for two-phase flow in single microfluidic channels through site-selective channel coating

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Publication details

The article was received on 08 Jan 2011, accepted on 17 Feb 2011 and first published on 15 Mar 2011


Article type: Technical Note
DOI: 10.1039/C1LC20012G
Lab Chip, 2011,11, 2030-2034

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    Multiple flow profiles for two-phase flow in single microfluidic channels through site-selective channel coating

    H. Logtenberg, M. J. Lopez-Martinez, B. L. Feringa, W. R. Browne and E. Verpoorte, Lab Chip, 2011, 11, 2030
    DOI: 10.1039/C1LC20012G

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