Issue 6, 2011

From plant to drug: ionic liquids for the reactive dissolution of biomass

Abstract

We present an ionic liquid (IL) strategy for the reactive dissolution of star anise seeds using different Brønsted-acidic ionic liquids as the solvent and reaction media towards the isolation of important pharmaceutical intermediates; this procedure provides a single-step, higher yielding and environmentally benign strategy towards the synthesis of the anti-influenza drug Tamiflu™.

Graphical abstract: From plant to drug: ionic liquids for the reactive dissolution of biomass

Supplementary files

Article information

Article type
Paper
Submitted
14 Jan 2011
Accepted
29 Mar 2011
First published
11 May 2011

Green Chem., 2011,13, 1442-1447

From plant to drug: ionic liquids for the reactive dissolution of biomass

A. K. Ressmann, P. Gaertner and K. Bica, Green Chem., 2011, 13, 1442 DOI: 10.1039/C1GC15058H

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