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Issue 6, 2011
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From plant to drug: ionic liquids for the reactive dissolution of biomass

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Abstract

We present an ionic liquid (IL) strategy for the reactive dissolution of star anise seeds using different Brønsted-acidic ionic liquids as the solvent and reaction media towards the isolation of important pharmaceutical intermediates; this procedure provides a single-step, higher yielding and environmentally benign strategy towards the synthesis of the anti-influenza drug Tamiflu™.

Graphical abstract: From plant to drug: ionic liquids for the reactive dissolution of biomass

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Supplementary files

Article information


Submitted
14 Jan 2011
Accepted
29 Mar 2011
First published
11 May 2011

Green Chem., 2011,13, 1442-1447
Article type
Paper

From plant to drug: ionic liquids for the reactive dissolution of biomass

A. K. Ressmann, P. Gaertner and K. Bica, Green Chem., 2011, 13, 1442
DOI: 10.1039/C1GC15058H

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