Issue 8, 2011

A new linker for solid-phase synthesis of heparan sulfate precursors by sequential assembly of monosaccharide building blocks

Abstract

A novel ester type linker which upon cleavage releases the glycans as carbamate protected aminoglycosides was successfully employed in the sequential assembly of L-idose and azido glucose monosaccharide building blocks to heparan sulfate precursors.

Graphical abstract: A new linker for solid-phase synthesis of heparan sulfate precursors by sequential assembly of monosaccharide building blocks

Supplementary files

Article information

Article type
Communication
Submitted
29 Oct 2010
Accepted
02 Dec 2010
First published
20 Dec 2010

Chem. Commun., 2011,47, 2390-2392

A new linker for solid-phase synthesis of heparan sulfate precursors by sequential assembly of monosaccharide building blocks

P. Czechura, N. Guedes, S. Kopitzki, N. Vazquez, M. Martin-Lomas and N. Reichardt, Chem. Commun., 2011, 47, 2390 DOI: 10.1039/C0CC04686H

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