Issue 19, 2010
From the journal:

Organic & Biomolecular Chemistry

Primary 1,2-diamine catalysis III: an unexpected domino reaction for the synthesis of multisubstituted cyclohexa-1,3-dienamines†

Junfeng Wang,a   Qin Li,a   Chao Qi,a   Yi Liu,a   Zemei Ge*a  and  Runtao Li*a  

* Corresponding authors

a State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing, P. R. China
E-mail: Lirt@mail.bjmu.edu.cn, Zmge@bjmu.edu.cn
Fax: +86-10-82716956
Tel: +86-10-82801504

Abstract

The first organocatalyzed multicomponent domino reactions of aryl ketones, aldehydes and malononitrile were carried out successfully to afford multisubstituted cyclohexa-1,3-dienamines in satisfactory yields.

Graphical abstract: Primary 1,2-diamine catalysis III: an unexpected domino reaction for the synthesis of multisubstituted cyclohexa-1,3-dienamines

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Article information

DOI
https://doi.org/10.1039/C0OB00089B
Article type
Communication
Submitted
06 May 2010
Accepted
18 Jul 2010
First published
09 Aug 2010

Org. Biomol. Chem., 2010,8, 4240-4242

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Primary 1,2-diamine catalysis III: an unexpected domino reaction for the synthesis of multisubstituted cyclohexa-1,3-dienamines

J. Wang, Q. Li, C. Qi, Y. Liu, Z. Ge and R. Li, Org. Biomol. Chem., 2010, 8, 4240 DOI: 10.1039/C0OB00089B

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