Issue 9, 2010
From the journal:

Molecular BioSystems

Modular blue fluorescent RNA sensors for label-free detection of target molecules†‡

Chika Furutani,a   Kazuki Shinomiya,a   Yasuhiro Aoyama,*a   Katsuhiro Yamadab  and  Shinsuke Sando*b  

* Corresponding authors

a Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, Japan
E-mail: aoyamay@sbchem.kyoto-u.ac.jp

b INAMORI Frontier Research Center, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka, Japan
E-mail: ssando@ifrc.kyushu-u.ac.jp

Abstract

A blue fluorescent RNA was applied to modular blue fluorescent RNA sensors, wherein a “recognition” event of the target molecule by the aptamer domain is transmitted through a “communication” module, to a “signaling” fluorescent RNA domain, which “lights up”.

Graphical abstract: Modular blue fluorescent RNA sensors for label-free detection of target molecules

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Article information

DOI
https://doi.org/10.1039/C001230K
Article type
Communication
Submitted
19 Jan 2010
Accepted
25 Feb 2010
First published
12 Mar 2010

Mol. BioSyst., 2010,6, 1569-1571

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Modular blue fluorescent RNA sensors for label-free detection of target molecules

C. Furutani, K. Shinomiya, Y. Aoyama, K. Yamada and S. Sando, Mol. BioSyst., 2010, 6, 1569 DOI: 10.1039/C001230K

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