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Issue 16, 2010
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Fluorescence enhancement of single DNA molecules confined in Si/SiO2 nanochannels

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Abstract

We demonstrate that the detected emission intensity from YOYO-labeled DNA molecules confined in 180 nm deep Si/SiO2 nanofunnels changes significantly and not monotonically with the width of the funnel. This effect may be of importance for quantitative fluorescence microscopy and for experiments with a tight photon budget.

Graphical abstract: Fluorescence enhancement of single DNA molecules confined in Si/SiO2 nanochannels

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Supplementary files

Article information


Submitted
06 Apr 2010
Accepted
28 May 2010
First published
14 Jun 2010

Lab Chip, 2010,10, 2049-2051
Article type
Communication

Fluorescence enhancement of single DNA molecules confined in Si/SiO2 nanochannels

F. Westerlund, F. Persson, A. Kristensen and J. O. Tegenfeldt, Lab Chip, 2010, 10, 2049
DOI: 10.1039/C004878J

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