Issue 7, 2010
From the journal:

Dalton Transactions

A new phosphonate pendant-armed cross-bridged tetraaminechelator accelerates copper(ii) binding for radiopharmaceutical applications†

Dannon J. Stigers,a   Riccardo Ferdani,b   Gary R. Weisman,*a   Edward H. Wong,*a   Carolyn J. Anderson,*b   James A. Golen,c   Curtis Moored  and  Arnold L. Rheingoldd  

* Corresponding authors

a Department of Chemistry, University of New Hampshire, Durham, New Hampshire, USA
E-mail: gary.weisman@unh.edu, ehw@cisunix.unh.edu

b Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA
E-mail: andersoncj@wustl.edu

c Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, USA

d Department of Chemistry and Biochemistry, University of Massachusetts, Dartmouth, North Dartmouth, Massachusetts, USA

Abstract

A phosphonate pendant-armed cross-bridged cyclam chelator has been synthesized, complexed to Cu(II), radiolabeled with 64Cu under mild conditions, and its biodistribution studied.

Graphical abstract: A new phosphonate pendant-armed cross-bridged tetraamine chelator accelerates copper(ii) binding for radiopharmaceutical applications

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Article information

DOI
https://doi.org/10.1039/B920871B
Article type
Communication
Submitted
08 Oct 2009
Accepted
26 Nov 2009
First published
15 Dec 2009
This article is Open Access

Dalton Trans., 2010,39, 1699-1701

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A new phosphonate pendant-armed cross-bridged tetraamine chelator accelerates copper(II) binding for radiopharmaceutical applications

D. J. Stigers, R. Ferdani, G. R. Weisman, E. H. Wong, C. J. Anderson, J. A. Golen, C. Moore and A. L. Rheingold, Dalton Trans., 2010, 39, 1699 DOI: 10.1039/B920871B

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