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Issue 32, 2010
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Selective binding and release of aspirin by an encapsulating receptor

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Abstract

The selective binding of aspirin deep inside superbowl synthetic hosts is reported. Evidence for a two-point binding mode of the drug by the host is presented. Both the strength of aspirin binding and the rate of its release are manipulated by altering the substituents about the host's aperture.

Graphical abstract: Selective binding and release of aspirin by an encapsulating receptor

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Publication details

The article was received on 16 Mar 2010, accepted on 08 Jun 2010 and first published on 05 Jul 2010


Article type: Communication
DOI: 10.1039/C0CC00422G
Citation: Chem. Commun., 2010,46, 5921-5923

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    Selective binding and release of aspirin by an encapsulating receptor

    T. V. Nguyen, H. Yoshida and M. S. Sherburn, Chem. Commun., 2010, 46, 5921
    DOI: 10.1039/C0CC00422G

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