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Issue 32, 2010
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Selective binding and release of aspirin by an encapsulating receptor

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Abstract

The selective binding of aspirin deep inside superbowl synthetic hosts is reported. Evidence for a two-point binding mode of the drug by the host is presented. Both the strength of aspirin binding and the rate of its release are manipulated by altering the substituents about the host's aperture.

Graphical abstract: Selective binding and release of aspirin by an encapsulating receptor

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Supplementary files

Article information


Submitted
16 Mar 2010
Accepted
08 Jun 2010
First published
05 Jul 2010

Chem. Commun., 2010,46, 5921-5923
Article type
Communication

Selective binding and release of aspirin by an encapsulating receptor

T. V. Nguyen, H. Yoshida and M. S. Sherburn, Chem. Commun., 2010, 46, 5921
DOI: 10.1039/C0CC00422G

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