Issue 20, 2009
From the journal:

Organic & Biomolecular Chemistry

Single-step enzymatic synthesis of (R)-2-O-α-d-glucopyranosyl glycerate, a compatible solute from micro-organisms that functions as a protein stabiliser†‡

Thornthan Sawangwan,a   Christiane Goedla  and  Bernd Nidetzky*a  

* Corresponding authors

a Institute of Biotechnology and Biochemical Engineering, Graz University of Technology, Petersgasse 12/1, Graz, Austria
E-mail: bernd.nidetzky@tugraz.at
Fax: +43 316 873 8434
Tel: +43 316 873 8400

Abstract

Regioselective glucosylation of R-glycerate catalysed by sucrose phosphorylase in the presence of sucrose as the donor substrate provided the natural compatible solute (R)-2-O-α-D-glucopyranosyl glycerate with complete regioselectivity in an optimised synthetic yield of 90% R-glycerate converted and a concentration of about 270 mM.

Graphical abstract: Single-step enzymatic synthesis of (R)-2-O-α-d-glucopyranosyl glycerate, a compatible solute from micro-organisms that functions as a protein stabiliser

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B912621J
Article type
Paper
Submitted
26 Jun 2009
Accepted
03 Jul 2009
First published
12 Aug 2009

Org. Biomol. Chem., 2009,7, 4267-4270

Permissions

Request permissions

Single-step enzymatic synthesis of (R)-2-O-α-D-glucopyranosyl glycerate, a compatible solute from micro-organisms that functions as a protein stabiliser

T. Sawangwan, C. Goedl and B. Nidetzky, Org. Biomol. Chem., 2009, 7, 4267 DOI: 10.1039/B912621J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements