Direct, facile synthesis of N-acyl-α-amino amides from α-keto esters and ammonia†
Abstract
N-Acyl-α-amino amides were prepared, without the necessity of chromatographic purification, in a single step by heating the corresponding α-keto
* Corresponding authors
a
Dept. of Chemistry & Biochemistry, University of Windsor, 401 Sunset Avenue, Windsor, Ontario, Canada
E-mail:
athadani@uwindsor.ca
Fax: 1 519 973-7098
Tel: 1 519 253-3000 ext. 3556
b
Departamento de Química, Centro de Investigación y de Estudios Avanzados, Avenida IPN 2508, Zacatenco 07360, México
E-mail:
jtiburcio@cinvestav.mx
Fax: +52 55 50613389
Tel: +52 55 50613721
N-Acyl-α-amino amides were prepared, without the necessity of chromatographic purification, in a single step by heating the corresponding α-keto
R. Ntaganda, T. Milovic, J. Tiburcio and A. N. Thadani, Chem. Commun., 2008, 4052 DOI: 10.1039/B808302A
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