Issue 20, 2006

Direct synthesis of tricyclic 5H-pyrido[3,2,1-ij]quinolin-3-one by domino palladium catalyzed reaction

Abstract

Unexpectedly, the palladium catalyzed coupling reaction of acrolein with 8-bromoquinoline gave 5H-pyrido[3,2,1-ij]quinolin-3-one in a single step.

Graphical abstract: Direct synthesis of tricyclic 5H-pyrido[3,2,1-ij]quinolin-3-one by domino palladium catalyzed reaction

Supplementary files

Article information

Article type
Communication
Submitted
31 Jul 2006
Accepted
04 Sep 2006
First published
18 Sep 2006

Org. Biomol. Chem., 2006,4, 3760-3762

Direct synthesis of tricyclic 5H-pyrido[3,2,1-ij]quinolin-3-one by domino palladium catalyzed reaction

S. Noël, C. Pinel and L. Djakovitch, Org. Biomol. Chem., 2006, 4, 3760 DOI: 10.1039/B611020G

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