Jump to main content
Jump to site search

Issue 10, 2006
Previous Article Next Article

Combinatorial receptor finding—large and random vs. small and focused libraries

Author affiliations

Abstract

Whereas in the classical combinatorial approach mainly large but completely random libraries are used, nowadays also the use of small but designed libraries is coming into focus. We discuss the pros and cons of these two different approaches, using examples from literature work and our own studies showing how combinatorial libraries are applied in supramolecular chemistry e.g. to identify artificial receptors for peptide binding in aqueous solvent.

Graphical abstract: Combinatorial receptor finding—large and random vs. small and focused libraries

Back to tab navigation

Publication details

The article was received on 18 Apr 2006, accepted on 10 Jul 2006 and first published on 23 Aug 2006


Article type: Perspective
DOI: 10.1039/B605731B
Citation: New J. Chem., 2006,30, 1377-1385
  •   Request permissions

    Combinatorial receptor finding—large and random vs. small and focused libraries

    C. Schmuck and P. Wich, New J. Chem., 2006, 30, 1377
    DOI: 10.1039/B605731B

Search articles by author

Spotlight

Advertisements