Issue 44, 2005
From the journal:

Chemical Communications

DNA-intercalation on pyrene modified surface coatings

Stephan Laib,†*a   Alexander Krieg,‡a   Pascal Häfligerb  and  Nikos Agorastosb  

* Corresponding authors

a Institute for Physical Chemistry, University of Zurich, Winterthurerstr. 190, 8057 Zurich, Switzerland
E-mail: slaib@physics.ucsd.edu

b Institute for Inorganic Chemistry, University of Zurich, Winterthurerstr. 190, 8057 Zurich, Switzerland

Abstract

Utilising the strong affinity between nucleic acids and an intercalating pyrene derivate, a novel efficient method for unspecific immobilisation of double-stranded DNA on to solid support for applications in bioanalytic, biophysics and microbiology is presented.

Graphical abstract: DNA-intercalation on pyrene modified surface coatings

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Article information

DOI
https://doi.org/10.1039/B511716J
Article type
Communication
Submitted
17 Aug 2005
Accepted
20 Sep 2005
First published
11 Oct 2005

Chem. Commun., 2005, 5566-5568

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DNA-intercalation on pyrene modified surface coatings

S. Laib, A. Krieg, P. Häfliger and N. Agorastos, Chem. Commun., 2005, 5566 DOI: 10.1039/B511716J

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