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A formal synthesis of (+)-lactacystin†
Abstract
A synthetic route to the neurotrophic agent (+)-lactacystin has been developed utilizing a base-promoted intramolecular alkylidenecarbene C–H insertion as the key transformation.
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Supplementary files
Article information
- Article type
- Communication
- Submitted
- 13 Jun 2005
- Accepted
- 09 Aug 2005
- First published
- 19 Sep 2005
Chem. Commun., 2005, 5106-5108
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A formal synthesis of (+)-lactacystin
D. J. Wardrop and E. G. Bowen, Chem. Commun., 2005, 5106 DOI: 10.1039/B508300A
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