Issue 10, 2004

A facile method for catalyst immobilisation on silica: nickel-catalysed Kumada reactions in mini-continuous flow and batch reactors

Abstract

An unsymmetrical salen-type nickel(II) complex was readily immobilised onto functionalised silica using a convenient tethering method. The supported complex was an effective recyclable heterogeneous catalyst in a room temperature cross-coupling reaction between 4-bromoanisole and phenylmagnesium chloride. Leaching of the metal into solution from the supported catalyst proved almost negligible. The silica-supported catalyst was ideal for use in a mini-continuous flow reactor since it did not exhibit swelling which is common and a problem for organic polymer resin supports.

Graphical abstract: A facile method for catalyst immobilisation on silica: nickel-catalysed Kumada reactions in mini-continuous flow and batch reactors

Article information

Article type
Paper
Submitted
06 Apr 2004
Accepted
15 Jul 2004
First published
07 Oct 2004

Green Chem., 2004,6, 526-532

A facile method for catalyst immobilisation on silica: nickel-catalysed Kumada reactions in mini-continuous flow and batch reactors

N. T. S. Phan, D. H. Brown and P. Styring, Green Chem., 2004, 6, 526 DOI: 10.1039/B405203J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements