Issue 20, 2004
From the journal:

Chemical Communications

A novel strategy for the preparation of arylhydroxylamines: chemoselective reduction of aromatic nitro compounds using bakers' yeast†

Feng Li,a   Jingnan Cui,*a   Xuhong Qian*ab  and  Rong Zhanga  

* Corresponding authors

a State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, China
E-mail: jncui@chem.dlut.edu.cn
Fax: +86-411-83673488
Tel: +86-411-88993872

b Shanghai Key Laboratory of Chemical Biology, Shanghai, China
E-mail: xhqian@ecust.edu.cn
Fax: +86-21-64252603
Tel: +86-21-64253589

Abstract

Using bakers' yeast as a biocatalyst, the chemoselective reduction of aromatic nitro compounds bearing electron-withdrawing groups gave the corresponding hydroxylamines with good to excellent conversion under mild conditions.

Graphical abstract: A novel strategy for the preparation of arylhydroxylamines: chemoselective reduction of aromatic nitro compounds using bakers' yeast

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Article information

DOI
https://doi.org/10.1039/B408566C
Article type
Communication
Submitted
07 Jun 2004
Accepted
10 Aug 2004
First published
07 Sep 2004

Chem. Commun., 2004, 2338-2339

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A novel strategy for the preparation of arylhydroxylamines: chemoselective reduction of aromatic nitro compounds using bakers' yeast

F. Li, J. Cui, X. Qian and R. Zhang, Chem. Commun., 2004, 2338 DOI: 10.1039/B408566C

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