Issue 9, 2004
From the journal:

Chemical Communications

Novel fluorescent biosensor for pathogenic toxins using cyclic polypeptide conjugates†

Omowunmi A. Sadik‡*a  and  Fei Yana  

* Corresponding authors

a Department of Chemistry, State University of New York at Binghamton, P. O. Box 6000, Binghamton, NY 13902-6000, USA

Abstract

This work describes a two-step conjugate synthesis of a new fluorescent analog of microcystin-LR and its subsequent utilization for the development of an optical biosensor for cyanobacteria toxins. The biosensor concept is based on the competitive binding between the native microcystin and its fluorescent analog at immobilized alkaline phosphatase enzymes.

Graphical abstract: Novel fluorescent biosensor for pathogenic toxins using cyclic polypeptide conjugates

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Article information

DOI
https://doi.org/10.1039/B316057B
Article type
Communication
Submitted
08 Dec 2003
Accepted
09 Mar 2004
First published
01 Apr 2004

Chem. Commun., 2004, 1136-1137

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Novel fluorescent biosensor for pathogenic toxins using cyclic polypeptide conjugates

O. A. Sadik and F. Yan, Chem. Commun., 2004, 1136 DOI: 10.1039/B316057B

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