Issue 2, 2003

A facile synthesis of 1,4-benzothiazines under solvent free conditions

Abstract

A rapid, solvent free synthetic strategy for the oxidative cyclocondensation of 2-aminobenzenethiols and 1,3-dicarbonyls using a catalytic amount of hydrazine hydrate has been developed in order to obtain 2,3-disubstituted-1,4-benzothiazines in high yields (83–96%).

Graphical abstract: A facile synthesis of 1,4-benzothiazines under solvent free conditions

Article information

Article type
Paper
Submitted
04 Dec 2002
First published
13 Mar 2003

Green Chem., 2003,5, 278-279

A facile synthesis of 1,4-benzothiazines under solvent free conditions

S. B. Munde, S. P. Bondge, V. E. Bhingolikar and R. A. Mane, Green Chem., 2003, 5, 278 DOI: 10.1039/B212042A

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