Issue 15, 2003
From the journal:

Chemical Communications

A facile aminocyclization for the synthesis of pyrrolidine and piperidine derivatives†

Zhihui Shao,ab   Jingbo Chen,a   Yongqiang Tu,b   Liang Lia  and  Hongbin Zhang*a  

* Corresponding authors

a School of Pharmacy, Yunnan University, Kunming, Yunnan 650091, P. R. China
E-mail: zhang_hongbin@hotmail.com
Fax: 86-871-5035538
Tel: 86-871-5031119

b National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, Gansu 730000, P. R. China

Abstract

Bromination of an isolated double bond followed by aminocyclization furnishes a highly stereoselective protocol for the intramolecular formation of pyrrolidine and piperidine ring containing subunits that are presented in numerous biologically active natural products.

Graphical abstract: A facile aminocyclization for the synthesis of pyrrolidine and piperidine derivatives

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Article information

DOI
https://doi.org/10.1039/B304157C
Article type
Communication
Submitted
15 Apr 2003
Accepted
12 Jun 2003
First published
26 Jun 2003

Chem. Commun., 2003, 1918-1919

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A facile aminocyclization for the synthesis of pyrrolidine and piperidine derivatives

Z. Shao, J. Chen, Y. Tu, L. Li and H. Zhang, Chem. Commun., 2003, 1918 DOI: 10.1039/B304157C

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