Issue 23, 2002
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Isolation and structure of cyclosenegalins A and B, novel cyclopeptides from the seeds of Annona senegalensis

Alassane Wélé,a   Yanjun Zhang,a   Christelle Caux,a   Jean-Paul Brouard,a   Lionel Dubost,a   Catherine Guette,a   Jean-Louis Pousset,a   Mamadou Badianeb  and  Bernard Bodo*a  

* Corresponding authors

a Laboratoire de Chimie des Substances Naturelles, ESA 8041 CNRS, Muséum National d'Histoire Naturelle, 63 rue Buffon, 75005 Paris, France

b Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine et de Pharmacie, Université Cheikh Anta Diop Dakar-Fann, Sénégal

Abstract

Two new cyclopeptides, cyclosenegalin A, cyclo(Pro1-Gly2-Leu3-Ser4-Ala5-Val6-Thr7-) (1) and cyclosenegalin B, cyclo(Pro1-Gly2-Tyr3-Val4-Tyr5-Pro6-Pro7-Val8-) (2), have been isolated from the methanol extract of the seeds of Annona senegalensis Pers., along with the known cyclic peptide, glabrin A. The structures were elucidated on the basis of the MS/MS fragmentation, using a Q-TOF mass spectrometer equipped with an ESI source, chemical degradation and extensive 2D-NMR.

Graphical abstract: Isolation and structure of cyclosenegalins A and B, novel cyclopeptides from the seeds of Annona senegalensis

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B205035H
Article type
Paper
Submitted
23 May 2002
Accepted
11 Oct 2002
First published
11 Nov 2002

J. Chem. Soc., Perkin Trans. 1, 2002, 2712-2718

Permissions

Request permissions

Isolation and structure of cyclosenegalins A and B, novel cyclopeptides from the seeds of Annona senegalensis

A. Wélé, Y. Zhang, C. Caux, J. Brouard, L. Dubost, C. Guette, J. Pousset, M. Badiane and B. Bodo, J. Chem. Soc., Perkin Trans. 1, 2002, 2712 DOI: 10.1039/B205035H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements