Issue 22, 2001
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

The reactions of diacetylenic ketones with nitrogen nucleophiles; facile preparation of alkynyl substituted pyrimidines and pyrazoles

Jack E. Baldwin,*a   Gareth J. Pritchardb  and  Richard E. Rathmella  

* Corresponding authors

a The Dyson Perrins Laboratory, Oxford University, South Parks Road, Oxford, UK

b Department of Chemistry, Loughborough University, Epinal Way, Loughborough, UK
E-mail: jack.baldwin@chem.ox.ac.uk

Abstract

Alkynyl substituted pyrimidines and pyrazoles have been synthesized by cyclocondensations of diacetylenic ketones with amidines and hydrazines.

Graphical abstract: The reactions of diacetylenic ketones with nitrogen nucleophiles; facile preparation of alkynyl substituted pyrimidines and pyrazoles

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Article information

DOI
https://doi.org/10.1039/B108645F
Article type
Communication
Submitted
27 Sep 2001
Accepted
15 Oct 2001
First published
26 Oct 2001

J. Chem. Soc., Perkin Trans. 1, 2001, 2906-2908

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The reactions of diacetylenic ketones with nitrogen nucleophiles; facile preparation of alkynyl substituted pyrimidines and pyrazoles

J. E. Baldwin, G. J. Pritchard and R. E. Rathmell, J. Chem. Soc., Perkin Trans. 1, 2001, 2906 DOI: 10.1039/B108645F

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