Stereoselective construction of trans-1,2-benzooxadecaline frameworks by three-component cascade reactions of an α-phenethyl-β-borylallylsilane with aldehydesElectronic supplementary information (ESI) available: experimental details and spectral data. See http://www.rsc.org/suppdata/cc/b1/b102613p/

Abstract

Reactions of α-phenethyl-β-borylallylsilane with aldehydes afforded tricyclic trans-1,2-benzooxadecaline frameworks stereoselectively in the presence of Lewis acids via sequential incorporation of two different aldehydes followed by cationic cascade cyclization, ending up with intramolecular Friedel–Crafts reaction.