Issue 5, 2000

Intramolecular organolithium addition to indol-2(3H )-ones; an approach to the synthesis of pyrrolo[1,2-a]indoles and pyrido[1,2-a]indoles

Abstract

Cyclisation of 3 and 10 by lithium–halogen exchange followed by reduction with lithium aluminium hydride gives pyrrolo[1,2-a]indoles 11 and 13 respectively. Similar treatment of bromides 4a and 4b gives pyrido[1,2-a]indoles 12a and 12b.

Article information

Article type
Paper
Submitted
03 Dec 1999
Accepted
12 Jan 2000
First published
25 Feb 2000

J. Chem. Soc., Perkin Trans. 1, 2000, 769-774

Intramolecular organolithium addition to indol-2(3H )-ones; an approach to the synthesis of pyrrolo[1,2-a]indoles and pyrido[1,2-a]indoles

K. Jones and J. M. D. Storey, J. Chem. Soc., Perkin Trans. 1, 2000, 769 DOI: 10.1039/A909548I

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