A highly regio- and stereoselective synthesis of (Z
)-3-arylidene-2,3-dihydro-5H-1,4-benzodioxepin-5-ones and (Z
)-3-arylidene-1,2,3,5-tetrahydro-4,1-benzoxazepin-5-ones through palladium–copper catalysis
Abstract
Sodium 2-(prop-2′-ynyloxy)benzoate 1a reacted with the aryl iodides 2–10 in the presence of bis(triphenylphosphine)palladium(II) chloride,