Novel terpene-based chiral bis-α-aminooximes and the corresponding macrocycles: X-ray structure of a ring-fused 5,7-dioxa-1,4,8,11-tetraazacyclotrideca-3,8-diene derivative

Abstract

The treatment of (+)-3-carene nitrosochloride with 1,2-diaminoethane results in bis-α-aminoxime, which undergoes intramolecular cyclisation under phase-transfer conditions to yield an optically active macroheterocyclic compound with two carane moieties incorporated.