1-Ethoxyvinyl 2-furoate, an efficient acyl donor for the lipase-catalyzed enantioselective desymmetrization of prochiral 2,2-disubstituted propane-1,3-diols and meso-1,2-diols

Shuji Akai; Tadaatsu Naka; Tetsuya Fujita; Yasushi Takebe; Yasuyuki Kita

doi:10.1039/B003871G

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

1-Ethoxyvinyl 2-furoate, an efficient acyl donor for the lipase-catalyzed enantioselective desymmetrization of prochiral 2,2-disubstituted propane-1,3-diols and meso-1,2-diolsElectronic supplementary information (ESI) available: preparation of 1-ethoxyvinyl 2-furoate. See http://www.rsc.org/suppdata/cc/b0/b003871g/

Shuji Akai,^a Tadaatsu Naka,^a Tetsuya Fujita,^a Yasushi Takebe^a and Yasuyuki Kita*^a

Author affiliations

* Corresponding authors

^a Graduate School of Pharmaceutical Sciences, Osaka University, Yamada-oka, Suita, Osaka, Japan.
E-mail: kita@phs.osaka-u.ac.jp

Abstract

A novel acyl donor, 1-ethoxyvinyl 2-furoate, was found to produce the title reactions with high enantiotopic selectivity, high reactivity and stability of the products under various conditions.

Download options Please wait...

Supplementary files

Preparation of 1-ethoxyvinyl 2-furoate DOC (21K)

Article information

DOI: https://doi.org/10.1039/B003871G
Article type: Communication
Submitted: 15 May 2000
Accepted: 19 Jun 2000
First published: 21 Jul 2000

Download Citation

Chem. Commun., 2000, 1461-1462

Permissions

Request permissions

1-Ethoxyvinyl 2-furoate, an efficient acyl donor for the lipase-catalyzed enantioselective desymmetrization of prochiral 2,2-disubstituted propane-1,3-diols and meso-1,2-diols

S. Akai, T. Naka, T. Fujita, Y. Takebe and Y. Kita, Chem. Commun., 2000, 1461 DOI: 10.1039/B003871G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications

Abstract

Supplementary files

Article information

Download Citation

Permissions

1-Ethoxyvinyl 2-furoate, an efficient acyl donor for the lipase-catalyzed enantioselective desymmetrization of prochiral 2,2-disubstituted propane-1,3-diols and meso-1,2-diols

Social activity

Search articles by author

Spotlight

Advertisements