Synthetic Studies of Dihydroagarofuran Sesquiterpene: an Improved NBS–THF–H2O System for Stereoselective Construction of Tetrahydrofuran Moiety
Abstract
An improved aqueous NBS–THF system in a range of media has proved to be effective for stereoselective construction of the bromotetrahydrofuran moiety of dihydroagarofuran sesquiterpene polyesters from the corresponding β-hydroxyalkene.