A Novel Route to Stereoselective Synthesis of (4R,5S)-O-Acetylosmundalactone and (4S,5R)-O-Acetylosmundalactone
Abstract
A route has been developed for the enantioselective synthesis of (4R,5S)-O-acetylosmundalactone 1 and (4S,5R)-O-acetylosmundalactone 2 by using Sharpless kinetic resolution of the racemic 1-(2-furyl)ethanol 6 as a key step.