NMR, X-Ray and MS Investigations of Ethyl 2-Aroyl- and Ethyl 2-Arylcarbamoyl-4,5-dimethyl-1,2,3,6-tetrahydropyridazine-1-carboxylates: Flexible Multidentate Ligands

Abstract

The ¹H and ¹³C NMR spectral assignments of ethyl 2-aroyl-4,5-dimethyl-1,2,3,6-tetrahydropyridazine-1-carboxylates (1a–1h) and ethyl 2-arylcarbamoyl-4,5-dimethyl-1,2,3,6-tetrahydropyridazine-1-carboxylates (2a–2k) are given based on DQF COSY, ¹H,¹³C HMQC and ¹H,¹³C HMBC-measurements; the dynamics of the tetrahydropyridazine ring has been studied by ¹H, ¹H EXSY-technique and the structure of one congener (4′-methylphenyl-derivative, 2a) has been confirmed by X-ray structure analysis.