Realisation of highly stereoselective dihydroxylation of a cyclopentene in the synthesis of (–)-aristeromycin

Abstract

A 2-furyl group was used as a synthetic equivalent of the CH₂OH at the 4′ position of aristeromycin, and dihydroxylation of the cyclopentene possessing the furyl group proceeded highly stereoselectively to produce the key diol for the synthesis of (–)-aristeromycin.