Issue 10, 1999

Stereochemical preference for heterochiral coupling controls selectivity in competitive peptide synthesis

Abstract

Competitive activated couplings of N-phthaloyl amino acids with amino acid dimethylamides show little selectivity among substrates in respect of their sidechains, but a consistent and significant preference for heterochiral outcomes.

Article information

Article type
Paper

Chem. Commun., 1999, 941-942

Stereochemical preference for heterochiral coupling controls selectivity in competitive peptide synthesis

D. Birch, M. North, R. R. Hill and G. E. Jeffs, Chem. Commun., 1999, 941 DOI: 10.1039/A901730E

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