Total syntheses of O4,O9-dimethylstealthins A and C1
Abstract
O 12 -Acetyl-O4,O9-dimethylstealthin A (2-acetoxymethyl-11-amino-5-hydroxy-4,9-dimethoxybenzo[b]fluoren-10-one and O4,O9-dimethylstealthin C (11-amino-5-hydroxy-4,9-dimethoxy-2-methylbenzo[b]fluoren-10-one), methylated derivatives of potent radical scavengers produced by Streptomyces viridochromogenes, have been synthesized using Suzuki coupling as a key step.