Issue 12, 1998

A New and Selective Oxidising Reagent for Oligonucleotide Synthesis

Abstract

A mixture of carbon tetrachloride, N-methylmorpholine and water in acetonitrile serves as an excellent reagent for oxidation of nucleoside phosphite to nucleoside phosphates and has been successfully applied to the solid phase synthesis of d(CGTAAAATGG).

Article information

Article type
Paper

J. Chem. Res. (S), 1998, 804-805

A New and Selective Oxidising Reagent for Oligonucleotide Synthesis

K. J. Padiya and M. M. Salunkhe, J. Chem. Res. (S), 1998, 804 DOI: 10.1039/A805771K

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