Issue 23, 1998

Dramatic increase of the DNA cleavage activity of Cu(Clip-phen) by fixing the bridging linker on the C3 position of the phenanthroline units

Abstract

The synthesis of a new ligand with two phenanthrolines bridged on their C3 carbon by a serinol is reported; Cu(3-Clip-phen) cleaves DNA more efficiently than the parent Cu(2-Clip-phen) bridged on the C2 carbon.

Article information

Article type
Paper

Chem. Commun., 1998, 2597-2598

Dramatic increase of the DNA cleavage activity of Cu(Clip-phen) by fixing the bridging linker on the C3 position of the phenanthroline units

M. Pitié, B. Sudres and B. Meunier, Chem. Commun., 1998, 2597 DOI: 10.1039/A807807F

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