Issue 18, 1998

Synthesis of fluorine-containing cyclic amino acid derivatives via ring closing olefin metathesis

Abstract

New N-protected α-CF3 amino esters with two alkene chains (1,7-dienes 3 and 1,6-dienes 5) were reacted with the ring closing metathesis catalyst Ru[double bond, length half m-dash]CHPh(Cl)2(PCy3)2 to give the α-CF3 dehydropipecolinate and prolinate derivatives 6 and 7.

Article information

Article type
Paper

Chem. Commun., 1998, 2053-2054

Synthesis of fluorine-containing cyclic amino acid derivatives via ring closing olefin metathesis

S. N. Osipov, A. F. Kolomiets, C. Bruneau, M. Picquet and P. H. Dixneuf, Chem. Commun., 1998, 2053 DOI: 10.1039/A804792H

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