Issue 5, 1997
From the journal:

Journal of Chemical Research, Synopses

Short Synthesis of 14β-Acylaminocodeinones from the Cycloadducts of Thebaine and Acylnitroso Compounds

Ross I. Gourlay  and  Gordon W. Kirby  

Abstract

Thebaine 1 has been converted in four steps, via its cycloadducts 7 with acylnitroso compounds and the derived dimethyl ketals 8 or ethylene ketals 13, into 14β-acylaminocodeinones 5 (R′=Me), analgesics formerly prepared from 14β-aminocodeinone dimethyl ketal 3.

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Article information

DOI
https://doi.org/10.1039/A608557A
Article type
Paper

J. Chem. Res. (S), 1997, 152-153

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Short Synthesis of 14β-Acylaminocodeinones from the Cycloadducts of Thebaine and Acylnitroso Compounds

R. I. Gourlay and G. W. Kirby, J. Chem. Res. (S), 1997, 152 DOI: 10.1039/A608557A

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