Use of electrospray ionization mass spectrometry to characterize chiral reactive intermediates in a titanium alkoxide mediated sulfoxidation reaction

Abstract

The ESIMS technique, combined with ¹ H NMR evidence, provides a precise inventory of the catalytic Ti ^IV precursors and the characterization of the reactive peroxometal complex involved in enantioselective sulfoxidation employing the Ti ^IV –homochiral trialkanolamine–alkylhydroperoxide system.