The preparation of cyclic α-hydroxyalkyl α-amino esters, the ring size of which varies varies from 4 to 7 members, in enantiopure form is readily achieved by intramolecular alkylative cyclisation of oxazolidine precursors.
M. D. Andrews, A. G. Brewster, M. G. Moloney and K. L. Owen, J. Chem. Soc., Perkin Trans. 1, 1996, 227 DOI: 10.1039/P19960000227
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