The aza-Darzens reaction of the chiral enolate derived from bromoacetylcamphorsultam 1 with N-(diphenyl-phosphinyl)aryl- and tert-butyl-methanimines proceeds in good yield to give cis-N-(diphenylphosphinyl)aziridinylcarbonyl sultams with high de. Monochiral cis-aziridinecarboxylates may be obtained in acceptable yield by hydrolysis of these sultams.
A. A. Cantrill, L. D. Hall, A. N. Jarvis, H. M. I. Osborn, J. Raphy and J. B. Sweeney, Chem. Commun., 1996, 2631 DOI: 10.1039/CC9960002631
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