A facile and direct entry to functionalised Neu5Ac2En derivatives from the methyl ketoside of Neu5Ac methyl esters
Abstract
Acetolysis of some methyl ketosides of N-acetylneuraminic acid (Neu5Ac) methyl esters, in a one-pot reaction, provides a rapid and efficient access to the corresponding 2,3-unsaturated Neu5Ac (Neu5Ac2en) derivatives.